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  1. Ian Wacogne
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The role of the clinician can be defined in a number of ways, but one of them must be sifting through signs and symptoms, and trying to work out whether they are meaningful or not. At first, I wrote ‘meaningful or just noise’, but then reflected that this implied a value judgement; of course, in paediatrics we're exquisitely aware that meaning is a consequence of your perspective. For us, a trivial symptom or sign may be the cause of profound concern to a parent—resulting in a serious shift in family dynamics, sleepless nights or unnecessary restrictions to family life. Two excellent papers in this edition give us some more to think about on this theme.

Khan, Hussain and Whitehouse give us a highly practical approach to the …

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