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- analgesics (non-narcotic)
- etomidate
- fractures (closed)
- hypnotics and sedatives
- manipulation (orthopaedic)
- midazolam
- pain
Di Liddo L, D'Angelo A, Nguyen B, et al. Etomidate versus midazolam for procedural sedation in pediatric outpatients: a randomized controlled trial. Ann Emerg Med 2006;48:433â40.
Clinical impact ratings Emergency medicine âââââââ Paediatrics (general) âââââââ
METHODS
Design:
randomised controlled trial.
Allocation:
concealed.*
Blinding:
blinded (patients, investigators, {data collectors, outcome assessors, and data analysts}†).*
Follow up period:
up to discharge.
Setting:
emergency department (ED) of a tertiary care paediatric hospital.
Patients:
100 patients 2–18 years of age (mean age 8.7 y, 50% boys) who presented to the ED with a displaced extremity fracture requiring sedation and analgesia for closed reduction. Exclusion criteria included respiratory tract infection, haemodynamic instability, recent head injury, known seizure disorder, heart or lung disease, craniofacial anomaly, adrenocortical dysfunction, …
Footnotes
Source of funding: Fonds d’opération pour les projects de recherche de l’Hôpital Ste-Justine.
Reproduced with permission from Evidence-Based Medicine 2007;12:77