Statistics from Altmetric.com
Q In adults and children with chronic asthma, is omalizumab (a recombinant humanised monoclonal anti-IgE referred to as rhuMAb-E25, rhu-Mab, or Xolair) better than placebo for clinical outcomes?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Respirology ★★★★★★☆ Paediatrics ★★★★★★☆ Allergy & immunology ★★★★★☆☆
Cochrane Airways Group Asthma and Wheeze trials register (up to February 2006), reference lists of relevant studies and review articles, all pharmaceutical companies producing anti-IgE formulations, 2 websites (www.fda.gov and www.clinicalstudyresults.org), meeting abstracts, and experts in the field.
Study selection and assessment:
randomised and blinded controlled trials (RCTs) in any language that included adults and children with chronic asthma and compared anti-IgE at any dose or route with placebo. 14 RCTs (n = 3143) met the selection criteria. Quality …
For correspondence: Dr S Walker Education for Health, Warwick, UK.
Source of funding: no external funding.
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.