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In children with moderate to severe atopic eczema, are wet wrap bandages more effective than topical ointments alone for maintenance treatment?
Clinical impact ratings GP/FP/Primary care ★★★★★★☆ Paediatrics ★★★★☆☆☆
randomised controlled trial.
blinded (scoring nurse).*
Follow up period:
a secondary care paediatric department at Fairfield General Hospital, Bury in Greater Manchester, UK.
50 children 3–60 months of age who were diagnosed with moderate to severe atopic eczema according to Hanifin and Rajka criteria, and had a severity rating of moderate or severe according to the SCORing Atopic Dermatitis (SCORAD) index (score ⩾ 15). Children with active skin infection at enrolment, previous allergic reactions to proposed trial treatments, or eczema predominantly on the face were excluded.
wet wraps (n = 28) or usual care (n = 22) for 4 weeks. Wet wrap bandages were initially applied 24 hours/day over 1% hydrocortisone ointment, and if necessary, topical steroids for 1 week. …
Dr D Hindley
Fairfield General Hospital, Bury, UK.
Source of funding: NHS Research and Development Fund.
Reproduced with permission from Evidence-Based Medicine 2006;11:108