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Evidence-based guideline for the management of decreased conscious level
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  • Published on:
    Gut and brain: the canaries of the body?

    Dear Editor,

    In a study of patients undergoing moderate and tepid hypothermic hemodiluted cardiopulmonary bypass cerebral oxygen saturation (RsO(2)) and mixed venous oxygen saturation (SvO(2)) were continuously monitored with a cerebral oximeter via a surface electrode placed on the patient's forehead and with the mixed venous oximeter integrated in the CPB machine, respectively. There was a poor correlation between...

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    Conflict of Interest:
    None declared.
  • Published on:
    Re: CO poisoning

    Dear Editor,

    In Duke et al' study of twenty consecutive children receiving extracorporeal life support for cardiovascular or respiratory failure the area under the ROC curve was 0.95 for DCO2 (and 0.88 for pHi). pHi and DCO2[difference between PCO2 in tonometer saline solution and arterial blood] predicted survival better than base deficit (area under ROC curve, 0.82), blood lactate level (0.29), arterial pH (0.65)...

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    Conflict of Interest:
    None declared.
  • Published on:
    Resus Room Poster

    Dear Editor,

    I have developed a poster that summarises the evidence-based guideline for the management of decreased conscious level developed by Richard Bowker and the Paediatric Accident and Emergency Research Group (PAERG). It was peer-reviewed and presented at the Inaugural Scientific Conference of the College of Emergency Medicine at Stamford Bridge, London in December 2006, and will probably be published in a...

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    Conflict of Interest:
    None declared.
  • Published on:
    Decreased conscious level: consider CO poisoning

    Dear Editor,

    Richard Bowker and the Paediatric Accident and Emergency Research Group are to be congratulated on their excellent guideline [1]. It appears comprehensive enough to detect all possible diagnoses while being concise enough to be workable. It does appear vulnerable in the area of poisoning, however.

    Carbon monoxide remains the most common cause of fatal poisoning in the UK [2], and should be...

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    Conflict of Interest:
    None declared.