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Delayed antibiotic prescription did not delay recovery in children with respiratory tract infections
  1. Eilidh Jane Stewart
  1. Royal Hospital for Children, Glasgow G51 4TF, UK
  1. Correspondence to Dr Eilidh Jane Stewart, Royal Hospital for Children, Glasgow G51 4TF, UK; e28.stewart{at}

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Study design: Randomised clinical trial.

Allocation: Centrally allocated via an online platform. Stratified by pathology and in blocks.

Setting: 39 primary care centres in Spain.

Patients: 436 children aged 2–14 years who presented to primary care with respiratory tract infections (RTIs).

Intervention: Patients diagnosed with an acute RTI were given either immediate (IAP), none (NAP) or delayed (DAP) antibiotic prescriptions. Antibiotic type was decided on by the prescribing doctor. A structured approach was used to deliver parent/patient education on the natural history of the disease and those given delayed prescriptions were given clear instructions on when to consider using the antibiotics.

Primary outcome: Symptom duration …

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  • Review of article Mas-Dalmau G, López CV, Gorrotxategi PG, et al. Delayed antibiotic prescription for children with respiratory infections: a randomized trial. Pediatrics 2021;147:e20201323.

  • Contributors EJS is the author of the abstract and commentary.

  • Provenance and peer review Not commissioned; internally peer reviewed.