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LMA was not superior to face-mask ventilation for neonatal resuscitation in term and later preterm infants born in Uganda
  1. Ayaz Ahmed,
  2. Joyce E O'Shea
  1. NICU, Royal Hospital for Children, Glasgow, UK
  1. Correspondence to Dr Ayaz Ahmed, NICU, Royal Hospital for Children, Glasgow, UK; ayaz.ahmed{at}

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Study design: Superiority randomised controlled trial.

Allocation: Cluster randomisation with face mask or laryngeal mask airway (LMA).

Blinding: Unblinded.

Setting: Single-site maternity hospital in Uganda.

Patients: Babies born in hospital requiring positive pressure ventilation with gestational age of 34 weeks and weight of greater than 2 kg. Exclusion criteria include stillbirths and infants with major malformations affecting airways or incompatible with life.

Intervention: Resuscitation by a midwife with face mask or LMA.

Outcomes: The primary outcomes were neonatal intensive care unit (NICU) admission with moderate to severe hypoxic ischaemic encephalopathy (HIE) on days 1–5 of hospitalisation and composite of neonatal death within 7 days. The secondary outcomes included the need for advanced resuscitation, very early neonatal death within 24 hours of life, early neonatal death within 7 days, any hospital admission during …

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  • Review of article Pejovic, Nicolas J., et al. A randomised trial of laryngeal mask airway in neonatal resuscitation. NEJM 2020;383;2138-47.

  • Twitter @ayaz74382348, @oshea_jem

  • Contributors AA wrote the abstract and commentary. JEO edited the commentary.

  • Provenance and peer review Not commissioned; internally peer reviewed.