Article Text

Download PDFPDF
Treatment with amoxicillin for 3 days for chest-indrawing pneumonia was non-inferior to treatment for 5 days in HIV-uninfected Malawian children
  1. Anna Athanasia Ntovolou1,
  2. Sarah Murphy2
  1. 1 Department of Paediatrics, Barking Havering and Redbridge Hospitals NHS Trust, Romford, UK
  2. 2 Department of Paediatrics, Mercy University Hospital, Cork, Ireland
  1. Correspondence to Dr Anna Athanasia Ntovolou, Department of Paediatrics, Barking Havering and Redbridge Hospitals NHS Trust, Romford RM7 0AG, UK; annaathanasia.ntovolou{at}

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Review of: Perkin MR, Bahnson HT, Logan K, et al. Association of early introduction of solids with infant sleep. A secondary analysis of a randomized clinical trial. JAMA Pediatr 2018;172:e180739.

Study design: This is a prospective, double-blinded, randomised, placebo controlled, non-inferiority trial.

Allocation: Randomisation was used with 1:1 ratio according to age group and trial phase, in blocks of 2, 4 or 6.

Study question

Setting: The setting was two hospitals in a malaria-endemic area of Malawi.

Patients: Patients studied were 3000 HIV-uninfected children, aged 2–59 months, who presented to the outpatient departments of the two sites and met the WHO criteria for the case definition of chest-indrawing pneumonia. Exclusion criteria included severe anaemia, severe respiratory distress at presentation, …

View Full Text


  • Twitter @anna_ntovolou

  • Contributors AAN wrote the abstract; SM wrote the commentary; and both approved the final version.

  • Provenance and peer review Not commissioned; internally peer reviewed.