Case history A previously healthy 11-year-old girl sustained a mosquito bite on her right cheek while on holiday in rural Bangladesh. A painless lump developed at the site, and over the ensuing 2 months gradually expanded. She was otherwise completely asymptomatic; there was no family history of note. On examination, there was obvious swelling affecting the right cheek and visible abnormality of the upper gum with displacement of the right upper central incisor (figure 1).
The facial swelling measured 4×5 cm, was firm to touch, non-fluctuant, painless and non-tender; no other abnormalities were present. Blood results at presentation are shown in box 1.
Blood results at presentation
Haemoglobin 132 g/L (115–155).
White cell count 6.92×109/L (5.0–13.0).
Erythrocyte sedimentation rate 7 mm/hour (0–12).
C-reactive protein 2 mg/L (0–10).
Calcium 2.32 mmol/L (2.1–2.6).
Alkaline phosphatase 242 u/L (78–213).
Lactate dehydrogenase 391 u/L (250–450).
MRI scan (figure 2) showed well-defined unilocular hyperintense signal cystic lesion measuring 40×38×40 mm involving right-sided alveolar process of maxilla completely filling the right maxillary sinus.
Question 1 What is the most likely diagnosis?
Solitary cystic ameloblastoma
Question 2 What is the appropriate next step?
Fine needle aspiration of cyst
Excision of lesion
Bone marrow aspiration
Magnetic resonance imaging of thorax and abdomen
Start intravenous ceftazidime
Answers can be found on page XX
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Collaborators Not applicable.
Contributors All authors have contributed equally to the manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.