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Interpretations
Clinician guide to COVID-19 diagnostics
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  • Published on: 20 January 2022
    History must not be allowed to repeat itself
    • oscar,m jolobe, retired geriatrician BMA, also a member(but not an affiliate) of the Manchester Medical Society

    In order to avoid repetition of the mistakes that have been made in the ascertainment of asymptomatic status in adults who might have COVID-19 infection(1) healthcare practitioners in paediatrics must ascertain the full currently known range of COVID-19 symptoms before a child is declared to be asymptomatic. In the event of an oligosymptomatic or monosymptomatic clinical presentation each of those children with sparse or atypical symptoms should be fully followed up to ascertain if the "stand alone" symptoms are "joined" by new symptoms or whether the oligosymptomatic status persists throughout the course of that child's illness.
    Finally, in conformity with the principles of Bayes' Theorem, frontline healthcare workers should be issued with a nomogram spelling out the post test probability of COVID-19 infection(2) in the event of a negative RT-PCR test result. The nomogram should be the subject of regular re-evaluation and updating, on the basis of new information about the authenticity of new symptoms reportedly associated with COVID-19.
    I have no funding and no conflict of interest
    References
    (1) Saurabh S., Vohra S
    What should be the criteria for determining asymptomatic status in COVID-19
    QJMed 2020;doi.org/10.1093/qjmed/hcab002 Article in Press
    (2) Chan GM
    Bayes theorem, Covid-19, and screening tests
    Amer J Emerg Med 2020;38:2011-2013

    Conflict of Interest:
    None declared.