Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Review ofVon Ungern-Sternberg BS, Sommerfield D, Slevin L, Drake-Brockman TFE, Zhang G, Hall GL. Effect of albuterol premedication vs placebo on the occurrence of respiratory adverse events in children undergoing tonsillectomies: the REACT randomized clinical trial. JAMA Pediatr 2019
Study design: Randomised, placebo-controlled trial. Participants were randomly allocated to an intervention using computer-generated block randomisation. Initially stratified based on administration method, but due to a change in practice favouring laryngeal mask airways over endotracheal tubes, in all ages, this was ceased.
Study question: To ascertain whether preoperative inhaled salbutamol reduces the rates of perioperative respiratory events in children undergoing tonsillectomies under general anaesthesia.
Setting: Perth Children’s Hospital, Western Australia.
Participants: 484 children, aged 0–8 years, undergoing general anaesthesia for tonsillectomy (+/− other ENT procedures including adenoidectomy).
Intervention: Preoperative administration of salbutamol (200 µg), administered via a metered …
Contributors AAT wrote and edited the abstract, and reviewed the final proof. AD wrote the commentary. RD wrote and edited the commentary.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Patient consent for publication Not required.
Provenance and peer review Not commissioned; internally peer reviewed.