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Fifteen-minute consultation: When medicines don’t work—the child with poorly controlled seizures


Drug-resistant epilepsy (DRE) occurs in 20%–30% of children with epilepsy with significant impact on their quality of life. Management of this group of children has greatly improved in the recent years with streamlining of epilepsy surgery services and associated quaternary multimodal evaluation. This article provides a review of DRE in children and management based on recent evidence and published opinion. We have also presented an algorithmic approach to the child with possible DRE.

  • drug-resistant epilepsy
  • refractory epilepsy
  • intractable epilepsy
  • antiepileptic drugs
  • epilepsy management

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