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Patients: 1.5 million young people (aged 16–25) examined prior to military service between 1967 and 1997.1
Exposure: Any history of childhood kidney disease, including structural anomalies and pyelonephritis.
Outcomes: Development of end-stage renal failure in adulthood.
Patient follow-up: Inclusion on the Israeli end-stage renal failure disease registry.
The study results are summarised in table 1.
A history of childhood renal disease, even if there is no evidence of renal impairment in adolescence, is associated with significantly increased risk of end-stage renal failure in adulthood.
1 Calderon-Margalit R, …
Provenance and peer review Not commissioned; internally peer reviewed.