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Fifteen-minute consultation: The child with an incidental finding of low IgA
  1. Adrienne Sullivan1,
  2. Ruth M Bland2,
  3. Rosie Hague3
  1. 1 Paediatric Department, Wishaw General Hospital, Wishaw, UK
  2. 2 General Paediatric Department, Royal Hospital for Children, Glasgow, UK
  3. 3 Paediatric Infectious Diseases and Immunology, Royal Hospital for Children, Glasgow, UK
  1. Correspondence to Dr Adrienne Sullivan, Paediatric Department, Wishaw General Hospital, Wishaw ML2 0DP, UK; adriennesullivan1{at}


Low or absent immunoglobulin A (IgA) levels are frequently found in children in whom immunodeficiency is not suspected. IgA deficiency is the most common primary immunodeficiency disorder in the UK affecting approximately 1 in 600 people. Isolated IgA deficiency is often identified coincidentally when investigating a child for conditions such as coeliac disease. The aim of this article is to provide a structured approach to the history, investigation and management of an isolated IgA deficiency.

  • immunoglobulin A deficiency
  • selective IgA deficiency

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  • All authors contributed equally to this paper.

  • AS, RMB and RH contributed equally.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.