Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Design: Randomised controlled trial.
Allocation: Computer generated block design.
Setting: Thirty-five paediatric intensive care unit (ICU) centres.
Patients: Three hundred and sixty patients (median age 5.5 years, IQR 1.4–12.5 years) in the lower target group; 353 patients (median age 6.7 years, IQR 1.7–12.8 years) in the higher target group.
Intervention: Randomisation to low target glycaemic control group (80–110 mg/dL (4.4–6.1 mmol/L)) or higher target glycaemic control group (150–180 mg/dL (8.3–10 mmol/L).
Outcomes: Primary outcome: number of ICU-free days to day 28. Prespecified secondary outcomes: 90-day mortality, severity of organ dysfunction, the number of ventilator-free days to day 28, incidence of healthcare-associated infection and incidence of hypoglycaemia.
Patient follow-up: Patients were followed up for 90 days. Recruitment stopped at …
Contributors AKL-H and KJR contributed equally to the preparation of the submitted manuscript.
Provenance and peer review Not commissioned; internally peer reviewed.