You are here

Article Text

Article menu
Download PDFPDF
Structured abstracts of sentinel articles: Picket
Gradual withdrawal of desmopressin in patients with enuresis leads to fewer relapses than an abrupt withdrawal
  1. Rebecca Amy Dalrymple1,
  2. Ian D Wacogne2
  1. 1 Department of Nephrology, Royal Hospital for Children, Glasgow, UK
  2. 2 General Paediatrics, Birmingham Children’s Hospital NHS Foundation Trust, Birmingham, UK
  1. Correspondence to Dr Rebecca Amy Dalrymple, Department of Nephrology, Royal Hospital for Children, 1345 Govan Road, Glasgow G51 4TF, UK; rebecca.dicks{at}doctors.org.uk

https://doi.org/10.1136/archdischild-2017-313000

Statistics from Altmetric.com

    Request Permissions

    If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

    Study question

    In children with enuresis, does gradual reduction of desmopressin compared with abrupt cessation result in less relapses?

    Study inclusion criteria: RCTs with a control group comparing gradual with abrupt cessation of desmopressin.

    Data source: Two independent reviewers searched Medline, Embase, ScienceDirect, Ovid, Google Scholar and Wiley Online Library for ‘desmopressin’ and ‘enuresis’. They searched for unpublished trials by contacting the authors. Risk of bias was assessed using recommendations from the Cochrane Collaboration. Four articles remained for meta-analysis and a further 18 were used in a systematic review.

    Outcome: Rate of sustained response (ie, no incidences of wetting) …

    View Full Text

    Footnotes

    • Contributors RAD wrote the abstract and commentary, and IDW edited both sections.

    • Provenance and peer review Not commissioned; internally peer reviewed.