Statistics from Altmetric.com
If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.
Setting: Patients recruited from 32 nephrology centres in Germany.
Patients: Any patient aged 18–70 years, with confirmed IgA nephropathy on biopsy, with proteinuria (>0.75 g/day), and hypertension (>139/89 mm Hg) or impaired renal function (estimated glomerular filtration rate end stage renal failure (eGFR) <90 mL/min/1.73 m2) or both.
Intervention: All patients joining the study had an initial 6 months ‘run-in’ period during which they received smoking cessation, non-steroidal anti-inflammatory drug avoidance, dietary advice and statins to reduce cholesterol to <5.2 mmol/L; and ACE inhibitor or angiotensin receptor blocker, to reduce proteinuria and hypertension.
If the proteinuria persisted (>0.75 and <3.5 g/day), participants were randomised to supportive treatment or one …
Correspondence to Dr Alexander D Lalayiannis, Nephrology Department, Birmingham Children's Hospital, Birmingham B4 6NH, UK;
Provenance and peer review Not commissioned; internally peer reviewed.