Article Text

Download PDFPDF
Bones, stones, moans and groans: hypercalcaemia revisited
  1. Ben C Reynolds1,
  2. Tim D Cheetham2
  1. 1Department of Paediatric Nephrology, Great North Children's Hospital, Newcastle-upon-Tyne, UK
  2. 2Department of Paediatric Endocrinology and Diabetes, Great North Children's Hospital, Newcastle upon Tyne, UK
  1. Correspondence to Dr Ben Christopher Reynolds, Department of Paediatric Nephrology, Great North Children's Hospital, Victoria Road, Newcastle-upon-Tyne NE1 4LP, UK; pinkdoc{at}


Disorders of calcium homeostasis are uncommon but important because of the broad spectrum of potential underlying causes that lie on a spectrum from the benign to the life-threatening. Paediatricians may find them challenging because they do not arise often enough for the investigative approach to be second nature. We report a 4-year-old with acute onset profound hypercalcaemia. We focus on an approach to the clinical problem that is based on the potential organ systems affected, namely the gut, bone and kidney. Key biochemical parameters that may help the paediatric team to reach a diagnosis are discussed, as well as important components of acute management.

  • Endocrinology
  • General Paediatrics
  • Nephrology

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.