Acute liver failure is a rare disorder with high mortality and resource cost. In the developing
world, viral causes predominate, with hepatitis E infection recognised as a common cause in …

Executive summary Liver disease in the UK stands out as the one glaring exception to the
vast improvements made during the past 30 years in health and life expectancy for chronic …

Hepatocyte transplantation has shown potential as an additional treatment modality for
certain diseases of the liver. To date, patients with liver-based metabolic disorders or acute …

OBJECTIVES: To determine short-term outcome for children with acute liver failure (ALF) as
it relates to cause, clinical status, and patient demographics and to determine prognostic …

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease
in children and adolescents in the United States, and most probably also in the rest of the …

The term acute liver failure (ALF) is frequently applied as a generic expression to describe
patients presenting with or developing an acute episode of liver dysfunction. In the context of …

Wilson's disease (WD) is a rare liver‐based disorder of copper metabolism. Prognostic
criteria described by our group in 1986 to predict death without transplantation have not …

Correspondence 390 www. thelancet. com/gastrohep Vol 7 May 2022 at least two different
mechanisms of action. Views were divided on the failure of immunomodulators, with 252 …

Previous studies have failed to identify mutations in the Wilson's disease gene ATP7B in a
significant number of clinically diagnosed cases. This has led to concerns about genetic …

The term non-alcoholic fatty liver disease (NAFLD), and its definition, have limitations for
both adults and children. The definition is most problematic for children, for whom alcohol …