User profiles for "author:Andrew Chapman"

Andrew R Chapman

- Verified email at ed.ac.uk - Cited by 5331

Andrew Chapman

- Verified email at i2cner.kyushu-u.ac.jp - Cited by 2547

PEGylated antibodies and antibody fragments for improved therapy: a review

AP Chapman - Advanced drug delivery reviews, 2002 - Elsevier
The use of covalent attachment of poly (ethylene glycol) to various different proteins in order
to modify their function has been reported over many years. One class of protein that this …

Laparoscopic adjustable gastric banding in the treatment of obesity: a systematic literature review

AE Chapman, G Kiroff, P Game, B Foster, P O'Brien… - Surgery, 2004 - Elsevier
BACKGROUND: We attempted to compare the safety and efficacy of laparoscopic
adjustable gastric banding with vertical-banded gastroplasty and gastric bypass. Morbid …

Assessment and treatment of patients with type 2 myocardial infarction and acute nonischemic myocardial injury

AP DeFilippis, AR Chapman, NL Mills, JA De Lemos… - Circulation, 2019 - Am Heart Assoc
Although coronary thrombus overlying a disrupted atherosclerotic plaque has long been
considered the hallmark and the primary therapeutic target for acute myocardial infarction …

Predictive accuracy of population viability analysis in conservation biology

BW Brook, JJ O'Grady, AP Chapman, MA Burgman… - Nature, 2000 - nature.com
Population viability analysis (PVA) is widely applied in conservation biology to predict
extinction risks for threatened species and to compare alternative options for their …

Global evaluation of echocardiography in patients with COVID-19

MR Dweck, A Bularga, RT Hahn, R Bing… - European Heart …, 2020 - academic.oup.com
Aims To describe the cardiac abnormalities in patients with COVID-19 and identify the
characteristics of patients who would benefit most from echocardiography. Methods and …

Therapeutic antibody fragments with prolonged in vivo half-lives

AP Chapman, P Antoniw, M Spitali, S West… - Nature …, 1999 - nature.com
Antibody fragments can be isolated rapidly using techniques such as phage display and can
be expressed to high levels in microbial systems. However, to date such antibody fragments …

[HTML][HTML] High-sensitivity cardiac troponin I at presentation in patients with suspected acute coronary syndrome: a cohort study

ASV Shah, A Anand, Y Sandoval, KK Lee, SW Smith… - The Lancet, 2015 - thelancet.com
Background Suspected acute coronary syndrome is the commonest reason for emergency
admission to hospital and is a large burden on health-care resources. Strategies to identify …

[HTML][HTML] Validation of a prediction tool for chemotherapy toxicity in older adults with cancer

A Hurria, S Mohile, A Gajra, H Klepin… - Journal of Clinical …, 2016 - ncbi.nlm.nih.gov
Purpose Older adults are at increased risk for chemotherapy toxicity, and standard oncology
assessment measures cannot identify those at risk. A predictive model for chemotherapy …

Long-term outcomes in patients with type 2 myocardial infarction and myocardial injury

AR Chapman, ASV Shah, KK Lee, A Anand, O Francis… - Circulation, 2018 - Am Heart Assoc
Background: Type 2 myocardial infarction and myocardial injury are common in clinical
practice, but long-term consequences are uncertain. We aimed to define long-term …

[HTML][HTML] High-sensitivity troponin in the evaluation of patients with suspected acute coronary syndrome: a stepped-wedge, cluster-randomised controlled trial

ASV Shah, A Anand, FE Strachan, AV Ferry, KK Lee… - The Lancet, 2018 - thelancet.com
Background High-sensitivity cardiac troponin assays permit use of lower thresholds for the
diagnosis of myocardial infarction, but whether this improves clinical outcomes is unknown …