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Imported childhood malaria: the Dublin experience, 1999–2006

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Abstract

Aims

Imported childhood malaria has never been studied in Ireland. We aimed to document the incidence and species of malaria in children presenting to paediatric hospitals in Dublin and to examine management and outcome measures.

Methods

Subjects were identified through laboratory archives from the three paediatric hospitals in Dublin. Clinical data were extracted retrospectively from clinical and laboratory records.

Results

As much as 67 episodes of malaria occurred in 66 children. Episodes occurred among new immigrants (n = 31) and Irish residents (n = 33) who travelled to endemic regions. The majority of those who travelled to endemic regions did not receive appropriate prophylaxis. Plasmodium falciparum was identified in 64 (95%) episodes, 26 with a parasite load above 2%. Eighteen children developed complications. All cases were treated successfully.

Conclusions

Irish health-care practitioners need to encourage malaria prophylaxis among travellers to malaria-endemic regions. Management guidelines should be formulated to assist Irish clinicians treating this potentially fatal illness.

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References

  1. Snow R, Craig H, Newton C, Steketee R (2003) The public health burden of Plasmodium falciparum malaria in Africa: deriving the numbers, working paper no 11. Bethesda MD Fogarty International Centre, National Institutes of Health, pp 1–75

  2. Jelinek T, Schulte C, Behrens R et al (2002) Imported falciparum malaria in Europe: sentinel surveillance data from the European network on surveillance of imported infectious diseases. Clin Infect Dis 34:572–576. doi:10.1086/338235

    Article  PubMed  CAS  Google Scholar 

  3. Ladhani S, Aibara RJ, Blaze M, Smith V, Shingadia DV (2006) Trends in imported childhood malaria in the UK: 1999–2003. Arch Dis Child 91:911–914. doi:10.1136/adc.2005.089433

    Article  PubMed  CAS  Google Scholar 

  4. Fleming P, Carroll A, Gordon E, Vaughan D (2006) Childhood malaria: an increasing problem in Irish paediatrics. Presented at the IPA annual scientific meeting, May 2006

  5. Lalloo DG, Shingadia D, Pasvol G et al (2007) for the HPA Advisory Committee on malaria prevention in UK travellers: UK malaria treatment guidelines. J Infect 54:111–121. doi:10.1016/j.jinf.2006.12.003

    Article  PubMed  Google Scholar 

  6. World Health Organisation (2006) World Health Organisation guidelines for the treatment of malaria. World Health Organisation

  7. Griffith KS, Lewis LS, Mali S, Parise ME (2007) Treatment of malaria in the United States: a systematic review. JAMA 297(20):2264–2277. doi:10.1001/jama.297.20.2264

    Article  PubMed  CAS  Google Scholar 

  8. British National Formulary for Children (2008) Anti-malarial prophylaxis. BMJ group, RPS publishing and RCPCH publications Ltd, London, vol 5.4.1, pp 390–394

  9. Williams JP, Chitre M, Sharland M (2002) Increasing Plasmodium falciparum in malaria in southwest London: a 25 year observational study. Arch Dis Child 86:428–430. doi:10.1136/adc.86.6.428

    Article  PubMed  CAS  Google Scholar 

  10. Maitland K, Nadel S, Pollard AJ, Williams TN, Newton CRJC, Levin M (2005) Management of severe malaria in children: proposed guidelines for the United Kingdom. BMJ 331:337–343. doi:10.1136/bmj.331.7512.337

    Article  PubMed  Google Scholar 

  11. Greenberg AE, Lobel HO (1990) Mortality from Plasmodium falciparum malaria in travelers from the United States, 1959 to 1987. Ann Intern Med 113(4):326–327

    PubMed  CAS  Google Scholar 

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Authors and Affiliations

  1. Department of Paediatrics, Children’s University Hospital, Temple Street, Dublin 1, Ireland

    A. Malikiwi & K. M. Butler

  2. Department of Clinical Microbiology, Children’s University Hospital, Temple Street, Dublin 1, Ireland

    M. Cafferkey

  3. Department of Paediatrics, Adelaide and Meath Hospitals, incorporating the National Children’s Hospital, Tallaght, Dublin 24, Ireland

    T. R. Leahy

  4. Department of Paediatric Infectious Diseases, Our Lady’s Children’s Hospital, Crumlin, Dublin 12, Ireland

    T. R. Leahy & K. M. Butler

  5. Division of Infectious Diseases, Hospital for Sick Children, 555 University Avenue, Toronto, ON, M5G 1X8, Canada

    T. R. Leahy

  6. The Royal College of Surgeons in Ireland, Dublin 2, Ireland

    M. Cafferkey

Authors
  1. T. R. Leahy
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  2. A. Malikiwi
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  3. M. Cafferkey
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  4. K. M. Butler
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Corresponding author

Correspondence to T. R. Leahy.

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Leahy, T.R., Malikiwi, A., Cafferkey, M. et al. Imported childhood malaria: the Dublin experience, 1999–2006. Ir J Med Sci 178, 329–332 (2009). https://doi.org/10.1007/s11845-009-0343-3

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  • DOI: https://doi.org/10.1007/s11845-009-0343-3

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