Quadruple therapy5
| Drug | Dosing | Duration | Side effects |
|---|---|---|---|
| Rifampacin | 10 mg/kg (maximum 450 mg if <50 kg or 600 mg if >50 kg) | 6 months | Liver toxicity |
| Isoniazid | 5–10 mg/kg (maximum 300 mg) | 6 months | Liver toxicity and peripheral neuropathy (common) |
| Pyrazinamide | 35 mg/kg (maximum 1.5 g if <50 kg or 2 g if >50 kg) | First 2 months | Liver toxicity |
| Ethambutol | 15 mg/kg once a day | First 2 months | Visual disturbance (colour blindness, loss of acuity and visual field loss) |