Cardiac | Hypotrophy, mitral valve prolapse, bradycardia, hypotension, orthostatic symptoms, long QT syndrome, arrhythmias, ventricular tachycardia, palpitations, general weakness, pitting oedema |
Renal | Decreased or increased urinary volume, renal failure, uraemia, renal calculi, hypovolaemic nephropathy, hypokalaemic nephropathy |
Respiratory | Reduced aerobic capacity |
Haematological | Anaemia, leucopoenia, thrombocytopaenia, bone marrow failure, increased infection risk |
Dental | Caries, erosion of dental enamel, erythema of the pharynx, enlarged salivary glands |
Gastrointestinal | Vomiting, abdominal pain, bloating, constipation, heartburn, haematemesis, involuntary vomiting |
Liver | Liver failure |
Metabolic | Fatigue, cold intolerance, diuresis, bone pain with exercise, arrested skeletal growth, abnormal temperature responses |
Endocrine | Arrested development of secondary sexual characteristics, amenorrhoea, higher rates of pregnancy complications, abnormal thyroid function, high cortisol, high growth hormone, hypoglycaemia, low luteinizing hormone and follicle-stimulating hormone |
Neurological | Apathy, poor concentration, muscle weakness, aches, cramps, myopathy |
Skin | Changes in hair, lanugo hair, dry skin, yellowing of skin |