Penicillin V (PCV) for 7 days (PCV7) or 3 days (PCV3) v placebo in children 4–15 years of age with a sore throat at 7 days*

Outcomes	Culture results	n	Comparison	Means	Difference between groups (95% CI)
*CI defined in glossary.
†Significant outcome favours placebo.
Duration of sore throat symptoms (d)	All children	156	PCV7 v placebo	3.8 v 3.8	0.0 (−0.9 to 0.9)
	All children	156	PCV3 v placebo	4.6 v 3.8	0.8 (−0.1 to 1.7)
	Positive for group A streptococci	96	PCV7 v placebo	3.0 v 3.5	−0.5 (–1.5 to 0.6)
	Positive for group A streptococci	96	PCV3 v placebo	4.8 v 3.5	1.3 (0.2 to 2.4)†
	Other or negative for group A streptococci	60	PCV7 v placebo	4.9 v 4.7	0.2 (−2.0 to 1.6)
	Other or negative for group A streptococci	60	PCV3 v placebo	4.4 v 4.7	–0.3 (–1.4 to 1.9)