Table 1

 Differential diagnosis considered and the investigations requested

DiagnosisInvestigation
CPK, creatine phosphokinase; CRP, C reactive protein; EBV, Epstein-Barr virus; ESR, erythrocyte sedimentation rate; FBC, full blood count; JIA, juvenile idiopathic arthritis; LFT, liver function test; U&E, urea and electrolytes.
LeukaemiaFBC and film
DermatomyositisCPK
JIAESR, CRP, FBC
Glandular feverEBV serology
HepatitisLFT
Renal impairmentU&E and creatinine
Endocrine disease, e.g. Addison’s or hypothyroidismU&E and thyroid function
DiabetesRandom glucose