PT - JOURNAL ARTICLE AU - Alexander Broomfield AU - Stephanie Grunewald TI - How to use serum ammonia AID - 10.1136/archdischild-2011-300194 DP - 2012 Apr 01 TA - Archives of disease in childhood - Education & practice edition PG - 72--77 VI - 97 IP - 2 4099 - http://ep.bmj.com/content/97/2/72.short 4100 - http://ep.bmj.com/content/97/2/72.full SO - Arch Dis Child Educ Pract Ed2012 Apr 01; 97 AB - Hyperammonaemia is a potentially extremely important indicator of impairment in intermediate metabolism. However, lack of experience in sample handling and confusion about what level is significant, can lead to its devaluation as a test. The aim of this article is to help the non-metabolic specialist to decide when it is appropriate to investigate for hyperammonaemia, to discuss potential investigatory pitfalls and to help in interpretation of results.