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Fifteen-minute consultation: The child with an incidental finding of low IgA
  1. Adrienne Sullivan1,
  2. Ruth M Bland2,
  3. Rosie Hague3
  1. 1Paediatric Department, Wishaw General Hospital, Wishaw, UK
  2. 2General Paediatric Department, Royal Hospital for Children, Glasgow, UK
  3. 3Paediatric Infectious Diseases and Immunology, Royal Hospital for Children, Glasgow, UK
  1. Correspondence to Dr Adrienne Sullivan, Paediatric Department, Wishaw General Hospital, Wishaw ML2 0DP, UK; adriennesullivan1{at}nhs.net

Abstract

Low or absent immunoglobulin A (IgA) levels are frequently found in children in whom immunodeficiency is not suspected. IgA deficiency is the most common primary immunodeficiency disorder in the UK affecting approximately 1 in 600 people. Isolated IgA deficiency is often identified coincidentally when investigating a child for conditions such as coeliac disease. The aim of this article is to provide a structured approach to the history, investigation and management of an isolated IgA deficiency.

  • immunoglobulin A deficiency
  • selective IgA deficiency

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Footnotes

  • All authors contributed equally to this paper.

  • AS, RMB and RH contributed equally.

  • Competing interests None declared.

  • Provenance and peer review Commissioned; internally peer reviewed.

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