Article Text

PDF
Picket
Introduction of allergenic foods from 3 months of age reduces incidence of food allergy in breastfed infants
  1. Rebecca A Dalrymple,
  2. Niten Makwana
  1. Department of Paediatrics, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK
  1. Correspondence to Dr Rebecca A Dalrymple, Department of Paediatrics, Sandwell and West Birmingham Hospitals NHS Trust, Birmingham, UK; rebecca.dicks{at}doctors.org.uk

Statistics from Altmetric.com

Study question

Patients: 1303 exclusively breastfed, well, singleton infants, aged 13–17 weeks recruited from the general population in England and Wales.

Early introduction group: Introduction of six allergenic foods: cow's milk, peanut, hen's egg, sesame, whitefish and wheat. Minimum amounts defined as 3 g once a week of at least five of the foods for 5 weeks between 3 and 6 months of age.

Standard introduction group: Continue to breast feed until 6 months of age, compliance defined as no consumption of allergenic foods including less than 300 mL of formula per day.

Outcomes: Challenge-proven food allergy to one or more of the six early introduction foods at age 1–3 years.

Analysis: Intention-to-treat (ITT) analysis and per-protocol analysis (PPA). In PPA, infants who were not compliant with their diet using the above definitions were excluded …

View Full Text

Request permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.