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Design: Prospective cohort of babies born through meconium stained amniotic fluid (MSAF) between 2003 and 2006.
Setting: Two teaching hospitals in The Hague, The Netherlands.
Patients: 394 term (>37/40) neonates were born through MSAF. The mean gestational age was 40 weeks, 56% were male, and mean birth weight was 3.5 kg.
Outcomes: Meconium aspiration syndrome (MAS) (respiratory distress, oxygen or mechanical ventilation requirement in the first 24 h of birth). Risk factors assessed included abnormalities of fetal heart trace, consistency of meconium, umbilical artery pH and 5 min Apgar score.
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