Arch Dis Child Educ Pract Ed 98:78 doi:10.1136/archdischild-2012-302610
  • What I have learnt from BMJ Case Reports

Interesting images – purple and white blobs!

  1. Beverley Almeida, E&P
  1. Department of Rheumatology, Great Ormond Street Hospital, London, UK
  1. Correspondence to Dr Beverley Almeida, Department of Rheumatology, Great Ormond Street Hospital, Great Ormond Street, London WC1N 3JH, UK; beverleyalmeida{at}

While reviewing for BMJ Case Reports I have found a wealth of interesting images, so I am drawing your attention to this case.

An extremely premature neonate developed fungal sepsis and despite antifungal therapy intensive care was withdrawn (figures 1 and 2). The appearance of fungal mycomas on cerebral ultrasound and postmortem (mycotic encephalitis) pathology samples are demonstrated. Postmortems for a proven infection are not common, so it is a valuable learning point to see this.

Figure 1

Bilateral widespread multiple spherical areas of increased echogenicity within the periventricular white matter and basal ganglia.

Figure 2

Multiple Candida granulomas within brain substance.


  • Provenance and peer review Not commissioned; internally peer reviewed.


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