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- Published on: 17 May 2011
- Published on: 22 June 2010
- Published on: 21 June 2010
- Published on: 6 May 2010
- Published on: 29 April 2010
- Published on: 17 May 2011Non infectious CRP elevation and correlation with gestational ageShow More
Non infectious CRP elevation and correlation with gestational age
Dear editor, We read with interest the discussion on the reliability of CRP as a sepsis marker in the newborn in the context of non infectious conditions following the interesting article on the use of CRP by McWilliam and Riordan (1). We have recently conducted an analysis on this topic including 690 newborns having CRP values done within the firs...
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None declared. - Published on: 22 June 2010How to use CRP - authors replyShow More
We were grateful to a number of people who contacted us about our article on How to use C - reactive protein [1].
Dr Abelian of Wrexham Maelor Hospital drew out attention to data on plasma half-life suggesting this was 19 hours in an adult [2] rather than the previously quoted 4-7 hours [3,4].
Dr Emmerson asked if there was robust data in support of the range of non infectious conditions quoted to cause...
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None declared. - Published on: 21 June 2010CRP is a useful marker in preterm infantsShow More
Dear Editors
Re: How to use: C-reactive protein. McWilliam, et al. 95:55-58
McWilliam and Riordan recently reviewed the use and limitations of C- reactive protein (CRP) in clinical practice, particularly in the diagnosis of infection.(1) The authors imply the authors suggest preterm infants cannot mount a CRP response (CRP levels remain low) when compared to term infants and older children. In the cont...
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None declared. - Published on: 6 May 2010CRP - a marker of systemic inflammationShow More
Dear Editor we read with interest the recent article regarding how to use C- reactive protein (CRP). While the authors discuss the role of CRP as a non-specific indicator of serious bacterial infection (SBI) they do not acknowledge that CRP is a non-specific indicator of systemic inflammation, the causes of which are many and varied with acute infective processes being only one.
It is important to consider alter...
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None declared. - Published on: 29 April 2010CRP and the Newborn InfantShow More
I was interested in the excellent article on How to use C-Reactive Protein in Education and Practice by McWilliam and Riordan. I was particularly interested in your comments in the article on Ruling in Sepsis and the comment that CRP is not diagnostic for sepsis in the neonate because it may be raised for other reasons. The article quotes - prolonged rupture of membranes - (most frequently caused by local sepsis and is...
Conflict of Interest:
None declared.