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Ondansetron as an aid to oral rehydration

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Although oral rehydration is generally regarded as best treatment for children with gastroenteritis, intravenous rehydration may be resorted to when the child vomits repeatedly. Antiemetics have been used but evidence of their value is limited. Researchers in Chicago (

) have used oral ondansetron (a serotonin3 (5H T3) agonist).

The trial took place in a children’s emergency department in 2004–5 and included 215 children aged 6 months to 10 years (mean 28 months) …

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