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Neonatal seizures—part 2: Aetiology of acute symptomatic seizures, treatments and the neonatal epilepsy syndromes
  1. Anthony R Hart1,2,
  2. Elizabeth L Pilling2,
  3. James J P Alix3
  1. 1Department of Paediatric and Neonatal Neurology, Sheffield Children's Hospital NHS Foundation Trust, Ryegate Children's Centre, Sheffield, South Yorkshire, UK
  2. 2Department of Neonatology, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
  3. 3Department of Clinical Neurophysiology, Sheffield Teaching Hospitals NHS Foundation Trust, Royal Hallamshire Hospital, Sheffield, UK
  1. Correspondence to Dr Anthony Hart, Department of Paediatric and Neonatal Neurology, Sheffield Children's Hospital NHS Foundation Trust, Ryegate Children's Centre, Tapton Crescent Road, Sheffield, South Yorkshire S10 5DD, UK; anthony.hart{at}sch.nhs.uk

Abstract

Most neonatal epileptic seizures are provoked by an underlying condition or problem—‘acute symptomatic seizures’. However, a few neonatal epilepsy syndromes exist, and these are defined by the constellation of seizure types, EEG findings and family history seen. Making an accurate diagnosis of an epilepsy syndrome can help direct investigations, treatment options and provide prognostic information. This article discusses the investigative approach and treatments for neonatal epileptic seizures, including the neonatal epilepsy syndromes.

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