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Best practice
Fifteen minute consultation: Managing neonatal and childhood herpes encephalitis
  1. K Le Doare1,
  2. Esse Menson2,
  3. Deepak Patel3,
  4. Ming Lim4,
  5. Hermione Lyall5,
  6. Jethro Herberg6
  1. 1Wellcome Trust/Imperial Centre for Global Health Research, Imperial College, London, UK
  2. 2Department of General Paediatrics, Evelina Children's Hospital, London, UK
  3. 3Imperial College NHS Trust, St Mary's Hospital, London, UK
  4. 4Department of Paediatric Neurology, Evelina Children's Hospital, London, UK
  5. 5Department of Paediatric Infectious Diseases and Immunology, Imperial College NHS Trust, St Mary's Hospital, London, UK
  6. 6Department of Paediatric Infectious Diseases, Section of Paediatrics, Imperial College, London, UK
  1. Correspondence to Dr Esse Menson, Evelina Children's Hospital, Westminster Bridge Road, London SE1 7EH, UK; esse.menson{at}gstt.nhs.uk

Abstract

Herpes simplex encephalitis (HSE) is the most common single cause of viral encephalitis in infants and children. Treated or untreated, it can be associated with considerable morbidity and mortality, and its presentation is usually insidious and non-specific. Prompt and careful investigation is important in order to establish the diagnosis so that treatment can be optimised. We address some common questions arising when diagnosing and treating presumed HSE throughout childhood.

  • Evidence Based Medicine
  • Immunology
  • Infectious Diseases
  • Neonatology
  • Neurology

This is an Open Access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/

https://doi.org/10.1136/archdischild-2014-306321

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