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Answers to Epilogue questions: Recurrent acute life-threatening events in a child with achondroplasia
  1. Mohamed O E Babiker1,
  2. Christopher Edwards2,
  3. Philip Davies2,
  4. Roddy O'Kane1,3
  1. 1Fraser of Allander Neurosciences Unit, Royal Hospital for Sick Children, Glasgow, UK
  2. 2Respiratory Department, Royal Hospital for Sick Children, Glasgow, UK
  3. 3Neurosurgery Department, Institute of Neurosciences, Southern General Hospital, Glasgow, UK
  1. Correspondence to Dr Mohamed O E Babiker, Fraser of Allander Neurosciences Unit, Royal Hospital for Sick Children, Dalnair Street, Yorkhill, Glasgow G3 8SJ, UK; mohamedbabiker{at}doctors.org.uk

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Answers

From the questions on page 19.

  1. Apnoea is usually multifactorial. In addition to central causes, such as cervicomedullary compression, mechanical causes include small thorax, narrow upper airways due to underdevelopment of the mid face and adenotonsillar hypertrophy. Risk of sudden death in achondroplastic children below 5 years was estimated in one study to be 50-fold higher than in the normal …

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