EVIDENCE-BASED MENTAL HEALTH
Honey, not dextromethorphan, was better than no treatment for nocturnal cough in children with upper respiratory infections.
| The first 150 words of the full text of this article appear below. |
STUDY DESIGN
randomised controlled trial.
{concealed*}
.
blinded (outcome assessors, patients and healthcare providers [to dextromethorphan (DM) and honey], {data collectors, data analysts, and manuscript writers}).*
a university-affiliated paediatric practice in Hershey, Pennsylvania, USA.
{108} children 2–18 years of age (median age 5 y, range 2–17 y, 53% girls) who had cough due to an upper respiratory infection (rhinorrhoea and cough for 
7 days) and whose parents scored 
3 points (somewhat) for 2 of 3 questions on a 7-point Likert scale that assessed cough and sleep difficulty (0 = not at all to 6 = extremely). Exclusion criteria included signs and symptoms of asthma, pneumonia, laryngotracheobronchitis, sinusitis, or allergic rhinitis; reactive airways disease; chronic lung disease; use of selective serotonin reuptake inhibitors; or use of an antihistamine or DM hydrobromide 6 hours from bedtime or DM polistirex 12 hours from bedtime on the day before or of enrolment.
1
Ostersund Hospital, Ostersund, Sweden, and Lovisenberg Deaconal University College, Oslo, Norway
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