EVIDENCE-BASED MENTAL HEALTH
Iron supplementation in non-anaemic women did not improve pregnancy outcomes and may be harmful to both mother and baby
| The first 150 words of the full text of this article appear below. |
STUDY DESIGN
randomised placebo-controlled trial.
unclear.*
blinded (patients and healthcare providers).*
STUDY QUESTION
6 prenatal clinics in Iran.
750 non-smoking women 17–35 years of age (mean age 26 y) with a singleton pregnancy in the early second trimester (mean 13 wks), haemoglobin concentration 
13.2 (mean 14.0) g/dl, body mass index 19.8–26 kg/m2, no history of threatened abortion in the current pregnancy, and no disease related to polycythaemia such as asthma or chronic hypertension.
ferrous sulphate, 150 mg (50 mg of elemental iron) (n = 375), or placebo (n = 375) once daily throughout pregnancy. All women received folic acid, 1 mg/day, but were not allowed to take other vitamin or mineral supplements.
small for gestational age (SGA, <10th percentile) infant, hypertensive disorder, premature labour, caesarean delivery for obstetrical reasons, Apgar score, birthweight, and perinatal mortality.
6 weeks after delivery.
97% (intention-to-treat analysis). 2 women in the placebo group were withdrawn because of the
Artemisia Prenatal Diagnosis Centre, Rome, Italy
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