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Treatment of anxiety
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It has been estimated that between 6% and 20% of American children suffer from anxiety (generalised anxiety disorder, separation anxiety and social phobia), but most of these children go undiagnosed and untreated. Both cognitive behavioural therapy (CBT) and treatment with selective serotonin-reuptake inhibitors (SSRIs) are effective. Now a study at six US centres (John T Walkup and colleagues. New England Journal of Medicine 2008;359:2753–66; see also Editorial, ibid: 2835–6) has confirmed the effectiveness of either treatment alone and shown that the combination of the two is better, at least in the short term.
A total of 488 children aged 7–17 years (mean 10.7 years, 74% <13 years of age) were randomised to age-adapted CBT (14 1-h sessions), sertraline (up to 200 mg per day), both, or placebo (2:2:2:1) for 12 weeks. All had a diagnosis of generalised or separation anxiety disorder or social phobia using the criteria of
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