BEST PRACTICE
Management of convulsive status epilepticus in children
1 Neurosciences Unit, Institute of Child Health, University College London and Great Ormond Street Hospital for Children NHS Trust, London, UK
2 Radiology and Physics Unit, Institute of Child Health, University College London, London, UK
3 MRC Centre of Epidemiology for Child Health, Institute of Child Health, University College London, London, UK
4 The National Centre for Young People with Epilepsy, Lingfield, Surrey, UK
Correspondence to:
Dr Michael Yoong, Department of Paediatric Neurosciences, The Wolfson Centre, Institute of Child Health, Mecklenburgh Square, London WC1N 2AP, UK; m.yoong@ich.ucl.ac.uk
| The first 150 words of the full text of this article appear below. |
Convulsive status epilepticus (CSE), with an incidence of 17–23 episodes per 100 000 children per year,1 is the most common medical neurological emergency in children. Since there is significant associated morbidity and mortality, which in part may be related to seizure length,2 it is essential that acute paediatric and paediatric emergency staff are comfortable and familiar with its management.
To maximise the probability of seizure termination, protocols for early appropriate treatment need to be developed. This review aims to examine the justification for early treatment and evidence supporting certain therapeutic interventions and to identify similarities and differences in protocols worldwide to identify and promote best practice.
DEFINITION
CSE is often defined as either two or more convulsions without complete recovery of consciousness between seizures (intermittent CSE) or a single prolonged seizure lasting at least 30 min (continuous CSE) with a motor component. The motor component usually consists of tonic stiffening followed
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