ARCHIMEDES
Question 3
SHOULD LYME DISEASE AFFECTING THE NERVOUS SYSTEM BE TREATED WITH ORAL OR INTRAVENOUS ANTIBIOTICS?
Musgrove Park Hospital, Taunton & Somerset NHS Trust, Taunton, UK; georginaselby@hotmail.com
Musgrove Park Hospital, Taunton, UK
Oxford University, Oxford, UK
| The first 150 words of the full text of this article appear below. |
A 10-year-old girl presents complaining of headache and muscle aches. She is diagnosed with a viral illness and sent home. Two days later she presents with a right sided facial paralysis and worsening headache. A CT scan is normal but her cerebrospinal fluid has a high lymphocyte count and a provisional diagnosis of Lyme neuroborreliosis is made, which is later confirmed on serology. The patient is commenced on a 3-week course of intravenous ceftriaxone. You wonder if there is any evidence to support managing this patient with oral antibiotics.
In children with Lyme neuroborreliosis (Lyme disease affecting the nervous system) [patient] are oral antibiotics [intervention] a comparable alternative to intravenous antibiotics [comparison] in inducing remission of symptoms [outcome]?
Primary sources
PubMed: "Lyme disease AND intravenous" yielded 180 hits, four of which were relevant and in the English language. "Lyme disease AND oral" yielded 184 hits, two of which were relevant
CiteULike 
Complore 
Connotea 
Del.icio.us 
Digg 
Reddit 
Technorati What's this?
- Full Text
- Full Text (PDF)
- Submit a response
- Alert me when this article is cited
- Alert me when eLetters are posted
- Alert me if a correction is posted
- Citation Map
Services
- Email this link to a friend
- Similar articles in ADC Online
- Similar articles in PubMed
- Add article to my folders
- Download to citation manager
- Request Permissions
Citing Articles
Google Scholar
PubMed
Topic Collections
-
Drugs: infectious diseases
-
Infection (neurology)
-
Headache (including migraine)
-
Pain (neurology)
-
Child health
Bookmark with
Register for free content
The full back archive is now available for all BMJ Journals. Institutional subscribers may access the entire archive as part of their subscription. Personal subscribers will also have access to all content when logged in. Non-subscribers who register have free access to all articles published before 2006 right back to volume 1 issue 1. Register here to access the free archive of all BMJ Journals.
Don't forget to sign up for content alerts so you keep up to date with all the articles as they are published.
