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Drugs used in childhood idiopathic or benign intracranial hypertension

Correspondence to:
Y Y Matthews, North East Wales NHS Trust, Wrexham Maelor Hospital; yim-yee.matthews@new-tr.wales.nhs.uk

The first 150 words of the full text of this article appear below.

Idiopathic intracranial hypertension (IIH) is a rare condition of increased intracranial pressure (ICP) without any identifiable pathology. Despite intervention, the clinical course of IIH is often prolonged and recurring with potentially serious complications of distressing headache and blindness.^1–10 Various therapeutic measures either alone or in combination have been used widely in children with IIH, however, their therapeutic efficacy has not been proven in controlled studies. This article provides a comprehensive review of clinical knowledge in childhood IIH and its various treatment modalities with an emphasis on the drugs used. It also highlights that current management is not evidence based and that well-designed multicentre randomised controlled trials are urgently needed.

	TERMINOLOGY

 
Idiopathic intracranial hypertension was first described in 1897¹¹ as "serous meningitis", followed by various names such as otitic hydrocephalus, toxic hydrocephalus, etc, pseudotumour cerebri,¹² and the commonly known benign intracranial hypertension.¹³ Subsequently, IIH was introduced¹⁴ and is now a preferred term . . . [Full text of this article]