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Archives of Disease in Childhood - Education and Practice 2008;93:1-8; doi:10.1136/adc.2004.066035
Copyright © 2008 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health

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BEST PRACTICE

Henoch–Schönlein purpura

E J Tizard1, M J J Hamilton-Ayres2

1 Department of Paediatric Nephrology, Bristol Royal Hospital for Children, Bristol, UK
2 Department of Paediatrics, Cheltenham General Hospital, Cheltenham, UK

Correspondence to:
Dr E J Tizard, Department of Paediatric Nephrology, Bristol Royal Hospital for Children, Upper Maudlin Street, Bristol BS2 8BJ, UK; jane.tizard@ubht.nhs.uk

The first 150 words of the full text of this article appear below.

Henoch–Schönlein purpura (HSP) is the commonest vasculitis of childhood. The first description of this disorder was probably that of a young boy with "bloody points" over the shins of his legs, abdominal pain, blood in the stools and urine and painful subcutaneous oedema, described by William Heberden in 1801. In 1837 Johann Schönlein described the association of purpura and joint pain as "Peliosis rheumatica". Eduard Henoch, Schönlein’s former student, noted gastrointestinal involvement in association with purpura and arthritis in 1868 and subsequently he recorded renal involvement too.1


*    DIAGNOSIS
 
Until recently the 1990 American College of Rheumatology criteria for HSP were the most commonly used criteria for diagnosis.2 This classification was modified but has now been superseded by the European League Against Rheumatism (EULAR) and Paediatric Rheumatology European Society (PReS) consensus criteria for the classification of childhood vasculitis. The group reached consensus that the classification of HSP should be the finding of . . . [Full text of this article]




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the riddle of the association of alpha 1-antitrypsin deficiency, henoch-schonlein purpura, and ANCA
oscar,m jolobe
Education and Practice Online, 5 Feb 2008 [Full text]



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