EVIDENCE-BASED MEDICINE
Review: children <2 years of age with bilateral acute otitis media and children with otorrhoea benefit most from antibiotics
Rovers MM, Glasziou P, Appelman CL, et al. Antibiotics for acute otitis media: a meta-analysis with individual patient data. Lancet 2006;368:1429–35.[CrossRef][Medline]
Q In children with acute otitis media (AOM), which subgroups of children benefit from treatment with antibiotics?
Clinical impact ratings GP/FP/Primary care
Infectious disease Surgery—ear nose throat Paediatrics
Keywords: anti-bacterial agents; otitis media
| The first 150 words of the full text of this article appear below. |
38° C), or both at 3–7 days. Secondary outcomes were pain and fever assessed separately, and adverse effects.
Overall, antibiotics reduced an extended course of AOM, pain, or fever (table). Subgroups of children <2
University of Southampton Southampton, UK
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