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Archives of Disease in Childhood - Education and Practice 2006;91:ep123
Copyright © 2006 BMJ Publishing Group Ltd & Royal College of Paediatrics and Child Health
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EVIDENCE-BASED MEDICINE

Wet wrap bandages for 4 weeks did not differ from topical ointments but increased skin infections in paediatric atopic eczema

Hindley D, Galloway G, Murray J, et al. A randomised study of "wet wraps" versus conventional treatment for atopic eczema. Arch Dis Child 2006;91:164–8.[Abstract/Free Full Text]

In children with moderate to severe atopic eczema, are wet wrap bandages more effective than topical ointments alone for maintenance treatment?

Clinical impact ratings GP/FP/Primary care ******{star} Paediatrics ****{star}{star}{star}

Keywords: dermatitis (atopic)

The first 150 words of the full text of this article appear below.


METHODS

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Design: randomised controlled trial.


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Allocation: unclear concealment.*


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Blinding: blinded (scoring nurse).*


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Follow up period: 1 month.


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Setting: a secondary care paediatric department at Fairfield General Hospital, Bury in Greater Manchester, UK.


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Patients: 50 children 3–60 months of age who were diagnosed with moderate to severe atopic eczema according to Hanifin and Rajka criteria, and had a severity rating of moderate or severe according to the SCORing Atopic Dermatitis (SCORAD) index (score >= 15). Children with active skin infection at enrolment, previous allergic reactions to proposed trial treatments, or eczema predominantly on the face were excluded.


Formula

IIntervention: wet wraps (n = 28) or usual care (n = 22) for 4 weeks. Wet wrap bandages were initially applied 24 hours/day over 1% hydrocortisone ointment, and if necessary, topical steroids for 1 week. Wet wraps were then applied for 12 or 24 hours/day, with hydrocortisone and emollients used during the non-wet wrap period. Usual . . . [Full text of this article]

Hywel Williams, PhD

University of Nottingham
Nottingham, UK






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